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THE LAUNCH SEQUENCE A new collection of 16 essays on how to accelerate AI for science & security: ifp.org/launch The AI revolution is already delivering enormous consumer benefits. But AI progress won't automatically solve humanity's most important problems first. To get the future we want, we need to shape the trajectory of AI progress. This series is a step toward that future…

12:13 PM · Aug 11, 2025

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, and

have an intro essay on how to actually shape AI progress:

Preparing for Launch | IFP

on how to map the mammalian brain’s connectome to solve fundamental problems in neuroscience, psychology, and AI robustness:

Mapping the Brain for Alignment | IFP

on how to incentivize AI for national priorities through a strategic challenge and evaluations program:

Benchmarking for Breakthroughs | IFP

4. Abel Brodeur & Bruno Barbarioli on how to build automated replication infrastructure for better, faster science:

The Replication Engine | IFP

on how block-grant labs can generate the real-world data AI needs to do science:

Teaching AI How Science Actually Works | IFP

on how to adapt our science funding mechanisms to the unique infrastructure needs of large-scale AI projects:

Using X-Labs to Unleash AI-Driven Scientific Breakthroughs | IFP

on how to turn the FDA’s data archive into faster clinical trials:

Biotech’s Lost Archive | IFP

on how to close the gap between AI-guided material design and real-world validation:

Scaling Materials Discovery with Self-Driving Labs | IFP

on how to build a large peptides database to train the AlphaFold for new antibiotics:

A Million-Peptide Database to Defeat Antibiotic Resistance | IFP

10.

on how to use privacy-preserving verification in the AI hardware stack to build trust and limit misuse:

Faster AI Diffusion Through Hardware-Based Verification | IFP

11.

on how to secure critical open-source code against memory safety exploits by automating code hardening at scale:

The Great Refactor | IFP

12.

on how to protect American AI from nation-state level threats:

A Sprint Toward Security Level 5 | IFP

13.

on how to generate the data necessary to reliably detect new pathogen outbreaks with AI:

Scaling Pathogen Detection with Metagenomics | IFP

14.

on how to ensure American AI models are robust and reliable via a DOD-led red- and blue-teaming effort:

Preventing AI Sleeper Agents | IFP

15.

on how to use AI and mathematics to prove and improve science and security:

The Infinity Project | IFP

16.

on how to leverage advanced AI to give defenders an asymmetric advantage in cybersecurity:

Operation Patchlight | IFP

17. The Launch Sequence also includes a fantastic list of statements from leaders across government, industry, and civil society about the importance of launching ambitious AI projects to advance science and security.

18. Erwin Gianchandani, the Assistant Director for Technology, Innovation and Partnerships at the National Science Foundation:

19. Kathleen Fisher, Director of DARPA’s Information Innovation Office (I20)

20. Statements from the leaders in civil society and industry:

21. You can read the whole series here:

The Launch Sequence | Institute for Progress

amazing work leading this project, sir

So many interesting essays in here, thanks for packaging up this effort. Excited to see what kind of funding efforts fall out of this.

glad you like it!

four seasons total carbon removal

@SexyLikeMeiosis

Aug 11

this reading list is gonna be delicious

Enjoy

excited to dig in, thank you for the effort!

Thanks for reading!

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Alec Stapp

@AlecStapp

Aug 11

Could download the PDFs!

Oak Security

@SecurityOak

Aug 11

Great to see science and security framed together! ambitious AI projects will need both in equal measure to succeed long term

Chris Anderson

@chr1sa

Aug 11

Any chance you can publish it as a Kindle book?

Would love to contribute something on AI for tech

Erik J.

@PrblmXpert

Aug 11

Strategic AI projects could redefine scientific discovery if we tackle structural barriers. The defensive tech focus is smart—how would you prioritize these initiatives?

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@cardworks

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We need an essay on AI driven labs for photonics from you,

Great, thanks!

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Caleb Watney

@calebwatney

Siri, is there a way to declare independence from a country for a second time?

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Luzia

@_revoluzia_

.@AndyMasley you’re desperately needed on the London tube!!

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Alec Stapp

@AlecStapp

This reminded me of another insane stat: 78% of noise complaints lodged against Ronald Reagan Washington National Airport were made by a single household.

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Alec Stapp

@AlecStapp

Aug 15

This is what’s wrong with our permitting system: A single NIMBY retiree can spend all her time suing to block wind & transmission projects from being built. Activists used these same rules to block nuclear projects in the 1970s. Now they’re being used against all clean energy.