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it might also help with Alzheimers?? Is modern medicine just the astronaut in the meme that's like "It's just insulin?" "always has been"
no it just turns out it really is that bad to be fat
skinny people can't reap the benefits/they already have
The paper says Osteoarthritis 
So it's probably not mostly about inflammation, probably more to do with the mechanical impact of weight loss
So it's probably not mostly about inflammation, probably more to do with the mechanical impact of weight loss
I have rheumatoid arthritis and coincidentally was on GLP1’s as my weight had gone past what I was physically able to lose. I recently stopped, my docs are now extremely worried because my rheumatoid arthritis accelerated. We believe wegovy stopped the disease from progressing.
Lol what? If you weigh less, there's less weight on your knees.
It's gravity, not magic.
My theory is that it addresses all the conditions associated with obesity. When they say they’re controlling for obesity and it still works, they’re in some way lying
The biggest issue with obesity is that it brings the body into a state of chronic inflammation and chronic physiological stress because the body thinks it’s constantly starving despite being obese
A lot of these benefits are linked by their involvement in inflammation
This is
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parm
@prmshra
Heard of Ozempic/Wegovy? These drugs are part of a class of medications called GLP-1 agonists.
In 2023, Science named GLP-1 agonists Breakthrough of the Year for their potential to combat "diabesity", 1 year after JWST won the same award. Let's ask why.
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There’s a book called The Keystone Approach by Rebecca Fett that outlines diets for every type of arthritis to eliminate all arthritis symptoms. You don’t need drugs. You can just remove the problem foods and eliminate your arthritis with zero side effects and zero extra cost.
Yes. It also has proven anti-gravity effects. After 1 year on GLP1, you weigh less on earth*
*not clinically tested yet on Moon, Mars or Venus.
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Yes because obesity is the major driver of most chronic diseases, and any drug that can produce dramatic weight loss is going to reduce the risk and severity of most major chronic diseases.
No, it just has a high lifetime customer value because the moment they go off of it,
everything reverts back to the way it was and it wreaks havoc on the human body.
So, once people start, they are stuck taking it for life.
Never underestimate the power of Big Pharma greed.
It’s a bit of a miracle but I think this one might be a cause and effect…lose weight and your knees feel better. No one should be shocked.
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It’s probably the weight loss, but there have been reported (but not yet studied) anti inflammatory effects.
No but our bodies over-processing sugars is anti-eternal life
It's implicated in cancer, neurodegenerative, cardio, inflammation, etc - the latter having a major effect on arthritis
Think its partially because those who experience significant weight loss see their inflammatory markers go down?
metformin is the same way. it's because metabolic disorder is responsible for a lot of disease.
The study looked at the effects of a drug called semaglutide on people with obesity and knee osteoarthritis. Obesity is a major risk factor for developing knee osteoarthritis, which can cause chronic pain and disability. Previous studies have shown that weight reduction can help
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I don't know which is worse, this title being AI-generated or written by a real journalist
yeah it's not that 'this fixes longevity' like direct telomere crap
it's 'this is a pragmatic hack and normal folk (if not researchers) are seriously into pragmatic hacks'
this also goes directly to something like this exchange:
FDA: "this doesn't exactly fully-cure something
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Now that there's a pill for it, suddenly the body positivity movement died out
Probably not but it does seem to have benefits on a wide number of chronic diseases.
Weight loss is life changing, not the drug. The drug is just effective at promoting weight loss.
Having a healthy weight and having top notch fitness is the key to a long life
I'm 100 lbs lighter, and what do you know, my knees don't hurt as much. Incredible
It definitely helps with inflammation. A lot of the body's issues start in the gut and that may be why the GLP1s are working for so many things.
Okay..admittedly, I've not read the article, but it's not exactly headline news that weight loss can positively impact knee pain (i.e. lead to decreased pain) which, in turn, makes it easier to move around and stay active.
Glp1 is a drug that reveals what many people have been shouting for decades: refined carbs are slow poisons.
Yes, it looks like it is a wonder drug in the same category as amphetamines, thalidomide and heroin.
It sure is the secret to my health insurance costs going up to cover all the folks taking those drugs.
