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we recently saw an insane discovery in biology, which if true, in my opinion, makes extraterrestrial life far far more likely. 🧵
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David Watson 🥑
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new research suggests that life on Earth became surprisingly complex very early, reshaping our understanding of life’s origins and its implications for the existence of life elsewhere in the universe.
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a paper about the Last Universal Common Ancestor (LUCA) hypothesis reconstructed the genome of our LUCA, dating it to about 4.2 billion years ago… …just a few hundred million years after Earth formed 4.5 billion years ago.
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4.2bn years ago historically was on the earlier end of any estimated age range for LUCA. however, this was the most reliable estimate using sophisticated estimation algorithms for Dr. Moody et al. crucially, they estimated the complexity of LUCA to be higher than anticipated.
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as per these new models, LUCA wasn’t some rudimentary organism it possessed a genome encoding approximately 2,657 proteins in a ~2.75 Mb genome (comparable to modern prokaryotes) this is unexpected because the popular consensus held that early life was far simpler
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^ reconstruction (A) LUCA was not necessarily the first life form, but its complexity suggests that life’s foundation systems (eg molecular synthesis, adaptation) evolved relatively quickly - under favorable conditions each finding challenges traditional views of evolution
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LUCA was an anaerobic acetogen, using hydrogen and carbon dioxide for energy via the Wood–Ljungdahl pathway—a sophisticated metabolic process still found in some microbes today. However, LUCA was part of an ecosystem and not an isolated entity.
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based on the reconstruction, LUCA wasn’t photosynthetic but demonstrated notable metabolic flexibility e.g. capable of both building its own molecules (autotrophy) and using those produced by others (heterotrophy) this adaptability is astonishing for such an ancient organism
on top of this, there is significant evidence for potential immunity already present at this point. the tl;dr is that LUCA was remarkably complex very soon into the formation of earth - millions of years in. which has interesting implications for astrobiology.
We always wonder how long life takes to evolve If such complex life truly evolved 400mn years into earth’s formation, it is unlikely to be the only form of life by this point. There was likely a molecular arms race* well in motion. Imagine what this means for other planets.
Advancements in astronomy have led to the identification of exoplanets with atmospheric compositions that could support life. JWST detected methane, maybe DMS and carbon dioxide in the atmosphere of K2-18 b, a planet located 124 light-years away - ie potential habitability
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similarly, JWST observations of WASP-39 b show the presence of CO2, providing insights into the planet’s formation and atmospheric composition.
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this already suggests that the building blocks of life, such as water and organic molecules, may be more common in the universe than previously thought - that piece of the puzzle had been recently solved.
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Specifically, a planet like k218b was formed ~2.5bn years ago. This is relatively young compared to earth - but empirically, we now know it may be old enough for complex life. Mars, formed around the same time as earth, could be estimated to have ancient microbes earlier too
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What are the next steps? While we do not have direct samples of LUCA, we can seriously use this information to figure out the answer to the following question:
if LUCA did adapt these fine tuned characteristics and phenotypes so so quickly, what, external to LUCA, could have caused this? Can it be other competing organisms? Specific molecules? Did a comet accelerate the development of ancient organisms on earth?
This, coupled with missions like JWST and Europa Clipper, will allow us to answer questions we only thought of in sci-fi movies.
*at a cellular level, this paper posits the following for LUCA: •Ribosomes for protein synthesis. •ATP synthase for energy production. •Likely a phospholipid membrane. •Evidence of an early immune system akin to CRISPR-Cas mechanisms. this indicates that LUCA coexisted with
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parm
@prmshra
Replying to @prmshra
4.2bn years ago historically was on the earlier end of any estimated age range for LUCA. however, this was the most reliable estimate using sophisticated estimation algorithms for Dr. Moody et al. crucially, they estimated the complexity of LUCA to be higher than anticipated.
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Gene based algorithms. A lot of mathematical modeling. But in the case of genes specifically math modeling ends up working very well
Without reading this, as an evolutionary biologist, I can tell you it’s going to completely speculative and based on the assumption that we have a LCUA, which is not known. Phylogeny is way more of a mess than imagined.
The study aims to understand the nature of the Last Universal Common Ancestor (LUCA), its age, and its impact on the early Earth system. LUCA is the oldest node on the tree of life from which the fundamental prokaryotic domains (Archaea and Bacteria) diverge. The researchers
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Fuck biology use math to prove it. P1) the universe is infinite P2) infinite universe mean there is a >0% chance anything exists P3) if everything you can think of exists, then 4D extraterrestrials exist C) there is a 4D being witnessing this interaction and laughing at us
Is there something about this discovery that suggests this evolution specifically took place on earth, as opposed to supporting a Panspermia hypothesis?
. What isn't mentioned is that this makes abiogenesis (life from non-life) much more difficult, due to the higher complexity of the first functional cells. Abiogenesis research is already on the ropes due to difficulty in generating basic starting molecules from inorganics...
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I think the assumptions about rate of genomic change/evolution that are baked in to such a model make the timeline very uncertain. Still, this is very cool.
If you aren't already familiar with the abiogenesis research of and Dave Deamer at I recommend it! Bruce is an old friend. I've been tracking this line of research for almost 15 years...the LUCA findings make perfect sense in light of their hypothesis.
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God just say it. Its panspermia, it's obviously panspermia. Either from mars or there's biological bits and pieces wafting through the cosmos on the regular. I'd bet my house on it at this point.
I always wonder what’s to stop organisms from existing on Venus. I understand the high temperatures would be a challenge but CO2 and lots of thermal energy should yield some kind of life.
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The more “sciences” search for, the more found. Or, one can go within, activate and use their third eye, and find every answer to every question within one year. It does take time to fix one’s chakra system, after all. Ask King Solomon about “aliens”. Spirits that are not
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Thanks for sharing! How can we tell if complex life form in the early days of Earth means that complex life is common and quick to develop vs complex life is rare and it was born somewhere else?
This is interesting! Seems to tie in with this research about life jumping from single cell to multi cellular in 2023
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dirtman (b/sac)
@terrorproforma
How hard is it for Multicellular life to develop? Turns out, E-Z. 600 days for yeast to go multicellular with distinct functional groups. All that was needed was a lack of oxygen that caused them to seek efficiencies in larger structures. One hard step eliminated for
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Are you uap pilled Parm? We've likely been visited thousands of years, if not longer, by extra/intra/ultraterrestrials. The Day After Roswell by Corso describes how we've recovered tech and used defense contractors to shield the program from public view.
If you have enough bio chemistry knowledge of the complexity of our body plus add up some research like this then the simplest most likely explanation is creation or panspermia but then you get to ask the same question for the planet of origin. This choice is possible only if you
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Super cool that LUCA is just 300M years after the moon forming impact theory. I used to be on team panspermia, but now I’m thinking there could have been a form of earlier bacteria prior to moon formation that survived underground. And this surviving bacteria could have
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It does open the question of where embryogeneis occurred — there must be a “mother planet” that’s the true home planet for not only all life on earth but for life on trillions of other planets. Wonder if it still exists today and what it looked like in its prime?
The waters (pun intended) are murky as geologists still debate when the Earth got its water. Some theories put it as late as 3.8 billion years ago, which is about 400 million after LUCA appeared. Otherwise, it is absolutely improbable that life is unique to Earth.
yeah it’s hard to say without a fossil record and knowing what exact method they used in this manuscript. Thanks for sharing your understanding of it. If I remember correctly, Cnidarians have been used as models for astrobiology experiments. Deep ocean and evolution for
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