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Novartis' new malaria treatment cured 97.4% of patients – more than the current best treatment It kills resistant parasites, too, and probably blocks transmission better than current drugs Approval is expected next year!

2:02 AM · Nov 13, 2025

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Samuel Hume

@DrSamuelBHume

Nov 13

More here: novartis.com/news/media-rel and here:

First new type of malaria treatment in decades shows promise against drug resistance

Wonderful news!

Impressive results from Novartis. Ganaplacide targets a novel mechanism that bypasses artemisinin resistance, which is critical as resistance mutations continue to spread.

this is awesome

Twice the speed, 99.9% less funding...

@OpenDroids

wins

0:29

That’s massive. 97% cure rate and kills resistant strains? Huge win for malaria treatment.

My Dad once had a "mild" case of malaria (he was on quinine as a preventative) & a "mild" case of the Flu at the same time. He said that he was so sick that he *actually* thought he was going to die. Malaria is serious stuff!

We should exterminate the anopheles mosquito anyway

great to have another option, but standard care already cures "94%" of cases, so this is an incremental movement. But again, great to have more options and variable mechanisms.

This does look like maybe an improvement over current treatments, but it's not earth shattering. It's incremental. The foe is not vanquished. It's just slightly weaker now. And all this is assuming you believe those numbers and that they bear out in the real world.

Jeff Lewis

@consultutah

Nov 13

this is the future we were promised

The real shame is that you have to wait until *next year* rather than right fucking now

So what is this "entirely novel mechanism" they write about?

@Grok

- let's see how you answer this, and how your answer compares to

Very exciting. Now has expanded use case. People forget high income countries buy as well for travel

God damn you western world!

That's incredible.

Wow! That's amazing!

Superb for all those malarial areas

Such a simple structure - ganaplacide.

Great news!!!!!!!

Now, let’s go in for the kill by developing the economy and creating a middle class.

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aaronshem

@aaronshem

Mar 11

Replying to @Craig_A_Spencer

You know what would really prevent the spread of diseases? Industrial scale power production as that people can afford single family homes, refrigeration, plumbing, individual bedrooms, screened windows, cattle industry that provides better nutrition & draws mosquitoes from x.com/aaronshem/stat…

Incredible progress elsewhere. Meanwhile, UK underfunding just pushes our best minds abroad. Until we fix that, we'll keep losing out on biotech breakthroughs like this.